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Mechanical valve

International Recommendations on Anticoagulation Levels following Heart Valve Replacement

Target INR Levels

Tissue valve

Indication Valve position European Society of Cardiology (1995) British Society of Haematology
AHA / ACC (1998)
Mechanical valves:        

First Generation

Starr Edwards, Bjork Shiley standard

  3.0 - 4.5 3.5 in all patients with mechanical prostheses 2.5 - 3.5

Second generation

St Jude, Medtronic Hall, BS Monostrut, Carbomedics

Aortic position 2.5 - 3.0 3.5 in all patients with mechanical prostheses 2.0 - 3.0
Mitral position 3.0 - 3.5 3.5 in all patients with mechanical prostheses 2.5 - 3.5
         
Bioprostheses in sinus rhythm Aortic position 2.5 - 3.0   Aspirin 80-100mg
Mitral position 3.0 - 3.5 2.5 Aspirin 80-100mg
  No anticoagulation after 3 months No anticoagulation after 3 months No anticoagulation after 3 months
         
Bioprostheses in atrial fibrillation Aortic position 3.0 - 4.5 2.5 2.0 - 3.0
Mitral position 3.0 - 4.5 2.5 2.5 - 3.5

For more information on different types of heart valve visit the Product forum of CTSNet.

Tissue valves

Mechanical valves



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